The Science of NooQ™: Why Your Cells Hold the Key to Sharp Performance, Strong Resilience, and Vital Longevity

You are made of approximately 37 trillion cells, and they do everything for you.

They think, move, repair, defend, and adapt. In fact, nearly 370 billion cells are replaced every day, in a constant cycle of cellular renewal powered by precision, energy, and raw biological building blocks.

But behind the scenes, your cells operate under intense pressure.

DNA gets damaged. Energy demands surge. Communication must remain flawless across trillions of microscopic systems.

And when this invisible system begins to strain, so do you:

- Performance slows

- Resilience fades

- Aging accelerates

At NooQ™, we believe that supporting your cells at the source isn’t just smart,  it’s essential.

That’s where nucleotides come in.

What Are Nucleotides and Why Do They Matter?

Nucleotides are small organic molecules made up of a nitrogenous base, a sugar (ribose or deoxyribose), and phosphate groups. Most people know them as the building blocks of DNA and RNA, but their role goes far beyond genetics. At NooQ™, we refer to them as your cell’s power bank.

The five key ribonucleotides, AMP, GMP, UMP, CMP, and IMP, are essential for:

• Cell proliferation

  Enabling cells to replicate and repair in high-turnover or challenged tissues.

• Energy production

  Driving cellular work and fuels performance

• Translation process

  Ensuring production of antibodies /immune protein production during immune challenge

• Intracellular Signaling

  Ensuring cellular adaptation to stress, hormone signaling, immune regulation, and brain function.

• Metabolic Support

  Support mitochondrial function and cellular energy under oxidative stress

How Does the Body Get Nucleotides?

Your body sources nucleotides in three main ways:

1. De-novo synthesis

   • Building them from scratch using amino acids, carbon dioxide, and formate

   • This process is ATP-intensive but flexible

2. Salvage pathways

   • Recycling broken-down DNA/RNA from cell turnover

   • Critical in fast-dividing or low-oxygen tissues

3. Dietary nucleotides

   • Found in meat, fish, and notably human breast milk

   • During periods of high demand (e.g. illness, intense training, injury), your body’s own supply may fall short — making dietary nucleotides conditionally essential

How Does the Body Benefit from Dietary Nucleotides?

Resilience: Strength Starts with the Immune System

Your immune system is your biological armor and dietary nucleotides help keep it strong.

• Support faster immune recovery after physical stress (within 150 minutes post-exercise)

• Enhance production of white blood cells, T-cells, and natural killer (NK) cells

• Speed up recovery from illness and reduce infection duration

And for gut resilience:

• Improve IBS symptoms by up to 8%

• Reduce stomach pain and promote healthy bowel movement

• Repair intestinal lining to maintain gut barrier integrity

• Support growth of beneficial gut bacteria and reduce inflammation

Performance: Fuel for Mind and Muscle

High-performers demand a lot from their bodies. Nucleotides help you keep up.

• Lower cortisol in response to stress

• Boost ATP production for fast energy without stimulants

• Reduce muscle damage and inflammatory markers after intense exercise

Longevity: Support That Lasts a Lifetime

True longevity isn’t just about living longer,  it’s about thriving at every stage.

Dietary nucleotides can play a role in slowing the biological clock:

• Reduce telomere loss caused by stress (3.5% vs. 12%)

• Improve cell turnover and decrease oxidative stress

• Enhance learning ability and protect against cognitive decline

• Slow epigenetic aging by an estimated 3 years within 19 weeks

Help Your Cells Do What They Do Best

Every NooQ™ formulation is designed around this simple but powerful truth:

When your cells thrive, you thrive.

By combining modern biotech with the intelligence of nature, we make it possible to enhance performance, increase resilience, and support long-term cellular vitality, not with trends, but with science that works at the source.

Power your cells.

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References

Ding T, Song G, Liu X, Xu M, Li Y. Nucleotides as optimal candidates for essential nutrients in living organisms: A review. J Funct Foods. 2021;82:104498., 10.1016/j.jff.2021.104498

Sterczala AJ, DuPont WH, Comstock BA, Flanagan SD, Szivak TK, Hooper DR, et al. Physiological effects of nucleotide supplementation on resistance exercise stress in men and women. J Strength Cond Res. 2016;30(2):569–78., 10.1519/JSC.0000000000001108.

Waititu SM, Yin F, Patterson R, et al. Dietary supplementation with a nucleotide-rich yeast extract modulates gut immune response and microflora in weaned pigs in response to a sanitary challenge. Animal. 2017;11(12):2156–64., 10.1017/S1751731117001276.

McNaughton L, Bentley DJ, Koeppel P. The effects of a nucleotide supplement on salivary IgA and cortisol after moderate endurance exercise. J Sports Med Phys Fitness. 2006;46(1):84–89., PubMed PMID: 16596104.

Wang S, et al. Nucleotides as an anti-aging supplementation in older adults: A randomized controlled trial (TALENTs). Adv Sci (Weinh). 2025; in press (early view)., 10.1002/advs.202417728